4G Smartphones with HTML5 will be able to function on the same level as desktop computers boosting the mobile casinos gambling options.
VALETTA, MALTA, January 15, 2011 -- The upcoming Consumer Electronics Show 2011 will showcase the new 4G Smartphones and the mobile casino gambling industry is keenly awaiting their arrival.
For some time now, mobile casinos software developers have been watching the growth of the mobile phone industry to see whether these devices could successfully support their games and software. Now that it is clear that mobile casinos can be enjoyed from the new devices hitting the market, developers are more confident to make good on their promise that we will see a substantial increase in new mobile games by this summer.
Those 4G Smartphones with HTML5 will be able to function on the same level as desktop computers, allowing gamblers to play on browser powered casinos and removing the need for them to download casino apps. In addition, faster wireless networks and improved systems will ensure that gamblers enjoy advanced mobile gaming experiences from wherever they may be.
There has been a sharp increase of revenues in smart phone and mobile casinos revenues across the board, and with these kinds of statistics, it is no wonder that mobile gamblers are excited about what the future holds for them.
About Casino Bonus Map:
Mobile Casino Map is a comprehensive online gambling portal that brings players up to date information regarding the latest incentives running at top mobile casinos. The site reviews these mobile casinos, mobile bingos, mobile poker sites and provides information regarding mobile casino games. Advice on game strategies, as well as gambling news is also provided.
Contact:
Arthur Prudent
Casino Bonus Map
Marketing Manager
136 Churchfield Road
London, England
United Kingdom W3 6BS
Tel: 02089923588
E-Mail: press@casino-bonus-map.com
Web: http://www.mobile-casino-map.mobi
Secrets To Finding Inner Happiness When Exploring A More Confident Mind, Or Retirement, And Ideas to Prevent Loneliness
The e-book will help uncover the real you, and help you discover the successful, self-actualized person you are meant to be.
CRESTON, BC, January 15, 2011 -- Digital Mind Coach E-Books …Written By Perry Ritthaler, Published By Davis E-Book Publishing.
Secrets To Finding Inner Happiness When Exploring A More Confident Mind, Or Retirement, And Ideas to Prevent Loneliness
http://www.digitalmindcoach.ca $8.95 Canada 4.5 MB
Psychology - Self-Help - Over 60 Beautifully Full Colored Illustrations To Comfort The Mind - The Secrets To Finding Inner Happiness can be discovered through a few simple steps of Psycho-Cybernetics, Neuro Linguistic Programming, and visual photographic stimulation. This amazing e-book has it all and will deliver to you the most powerful and unique combination of psychological procedures to obtaining inner happiness known in the world today. This incredible e-book does not stop at just helping you obtain inner happiness, it continues to tell you how to obtain a happier retirement and discovering the greatest secret of all - how to prevent loneliness.
“Secrets to Finding Inner Happiness through Exploring a More Confident Mind, Planning a Happier Retirement, and Ideas to Prevent Loneliness” is a self-help e-book which takes you on a journey of self-discovery and personal development.
The e-book will help uncover the real you, and help you discover the successful, self-actualized person you are meant to be. The objective of the e-book is to increase your level of happiness through self-discovery.
Your objective is to create your own happiness. Only you know what that means to you…you help yourself with fresh ideas and experience the reward of a strong wellbeing and genuine happiness working with this e-book.
If you are happy and leading a fulfilling life, those around you will be happier too!
We ALL have the potential for happiness, and we all deserve to be happy. We make millions of choices throughout our lives, and the net result of all these choices combined, determines our level of true happiness. This is why “Secrets to Finding Inner Happiness through Exploring a More Confident Mind, Planning a Happier Retirement, and Ideas to Prevent Loneliness” is so valuable to you. Your life manual e-book not only provides ideas, and methods of achieving happiness; it does so in an absorbing, easily readable style through pictures on every page.
The goal of this e-book is to share with you how to accelerate the changes you want in your life and help you become a happier you starting right now.
Today is the perfect time to purchase this fantastic self-help e-book and start the process of becoming a new and better you.
Download your free sample e-book today.
Digital Mind Coach Promotion
We've Got More Value For You To Enjoy
More e-books. More fun. More value. Right now, there’s more of everything at Digital Mind Coach.
Limited time offer, purchase two Digital Mind Coach e-books and get the third Digital Mind Coach e-book free.
Get more value with a discount.Limited Time Offer 33% Off.
Press Contact:
Perry Ritthaler
Digital Mind Coach
Writer
105-406-16th ave n
Creston, BC
Canada v0b 1g5
Tel: 2504285232
E-Mail: perry.ritthaler@digitalmindcoach.com
Web: http://www.digitalmindcoach.ca
CRESTON, BC, January 15, 2011 -- Digital Mind Coach E-Books …Written By Perry Ritthaler, Published By Davis E-Book Publishing.
Secrets To Finding Inner Happiness When Exploring A More Confident Mind, Or Retirement, And Ideas to Prevent Loneliness
http://www.digitalmindcoach.ca $8.95 Canada 4.5 MB
Psychology - Self-Help - Over 60 Beautifully Full Colored Illustrations To Comfort The Mind - The Secrets To Finding Inner Happiness can be discovered through a few simple steps of Psycho-Cybernetics, Neuro Linguistic Programming, and visual photographic stimulation. This amazing e-book has it all and will deliver to you the most powerful and unique combination of psychological procedures to obtaining inner happiness known in the world today. This incredible e-book does not stop at just helping you obtain inner happiness, it continues to tell you how to obtain a happier retirement and discovering the greatest secret of all - how to prevent loneliness.
“Secrets to Finding Inner Happiness through Exploring a More Confident Mind, Planning a Happier Retirement, and Ideas to Prevent Loneliness” is a self-help e-book which takes you on a journey of self-discovery and personal development.
The e-book will help uncover the real you, and help you discover the successful, self-actualized person you are meant to be. The objective of the e-book is to increase your level of happiness through self-discovery.
Your objective is to create your own happiness. Only you know what that means to you…you help yourself with fresh ideas and experience the reward of a strong wellbeing and genuine happiness working with this e-book.
If you are happy and leading a fulfilling life, those around you will be happier too!
We ALL have the potential for happiness, and we all deserve to be happy. We make millions of choices throughout our lives, and the net result of all these choices combined, determines our level of true happiness. This is why “Secrets to Finding Inner Happiness through Exploring a More Confident Mind, Planning a Happier Retirement, and Ideas to Prevent Loneliness” is so valuable to you. Your life manual e-book not only provides ideas, and methods of achieving happiness; it does so in an absorbing, easily readable style through pictures on every page.
The goal of this e-book is to share with you how to accelerate the changes you want in your life and help you become a happier you starting right now.
Today is the perfect time to purchase this fantastic self-help e-book and start the process of becoming a new and better you.
Download your free sample e-book today.
Digital Mind Coach Promotion
We've Got More Value For You To Enjoy
More e-books. More fun. More value. Right now, there’s more of everything at Digital Mind Coach.
Limited time offer, purchase two Digital Mind Coach e-books and get the third Digital Mind Coach e-book free.
Get more value with a discount.Limited Time Offer 33% Off.
Press Contact:
Perry Ritthaler
Digital Mind Coach
Writer
105-406-16th ave n
Creston, BC
Canada v0b 1g5
Tel: 2504285232
E-Mail: perry.ritthaler@digitalmindcoach.com
Web: http://www.digitalmindcoach.ca
Discover How To Control Ideas, Decisions And Affirmations
“Discover How to Control Ideas, Decisions and Affirmations” is a training manual which can help you move your life in a steadily positive successful direction.
CRESTON, BC, January 15, 2011 -- Digital Mind Coach E-Books …Written By Perry Ritthaler, Published By Davis E-Book Publishing.
Discover How To Control Ideas, Decisions And Affirmations
http://www.digitalmindcoach.com $12.95 Canada 9.61 MB
Psychology - Self-Help - Over 120 Beautifully Full Colored Illustrations To Comfort The Thinking Mind- Learning how to control your ideas, your decisions, and your affirmations will quickly help you make positive, lasting and effective changes in your life, leading to personal empowerment, greater wealth, health and happiness. These are the most powerful psychological procedures for mind enhancement available in the world today.
Just by reading this e-book through a couple times, and with a little perseverance, you can build your confidence, increase your self-esteem, improve your mental focus and increase your ability to handle every day stress due to anxiety or tragedy. As importantly, you can greatly improve your performance in your work, enhance your everyday decision-making abilities, and elevate your mood in the process. Making the best decisions, having the best ideas, finalizing your affirmations, and gaining peace and comfort of mind are your final destination.
“Discover How to Control Ideas, Decisions and Affirmations” is a training manual which can help you move your life in a steadily positive successful direction. The affirmations and ideas presented here in pictures and text format are designed to enrich your life by opening the doors to the abundance of the Universe. This unique publication offer information and ideas which will help you to quickly make positive, effective and lasting changes in your life, leading to personal empowerment, and greater wealth, health and happiness.
The ideas are presented in such a way that positive thoughts soon become a natural part of your way of thinking. You will receive the benefits of a unique combination of the most powerful psychological procedures for mind enhancement available in the world today. The skills and techniques used in this e-book include advanced Psycho-Cybernetics and Neuro Linguistic Programming combined with Motivational Coaching.
By reading this e-book through a few times or so, and with a little perseverance, you can build your confidence, increase self-esteem, improve your mental focus and increase your ability to handle every day stress due to anxiety or tragedy. As importantly, you can greatly improve your performance in your work, enhance your everyday decision-making abilities, and elevate your mood in the process.
Imagine living the life you want!
If you can see it in your mind this e-book can help you make it a reality.
“Discover How to Control Ideas, Decisions and Affirmations” has been created to give people access to an internationally recognized approach to rapid behavioral change. The e-book can provide profound insights into the wealth of knowledge, wisdom and creativity that exists in each and every one of us. Through the use of this e-book people can lead more fulfilling, balanced and happier lives through understanding and utilizing the powerful motivating force of their subconscious mind.
Unlike life coaching, this e-book accesses the subconscious mind using pictures and written text to resolve issues quickly. The e-books offered through this web site are manuals to get more performance out of the brain and in doing so you can remove subconscious blocks, create a new belief system, tap into powerful resources and anchor your positive state of mind. It’s a powerful way to access your belief system and make the lasting changes you desire. Imagine feeling more empowered and having the mental tools to feel so much better.
The purpose of this e-book is to teach you how to accelerate the changes you want in your life and start becoming a better you by tomorrow.
Download your free sample e-book today.
Digital Mind Coach Promotion
We've Got More Value For You To Enjoy
More e-books. More fun. More value. Right now, there’s more of everything at Digital Mind Coach.
Limited time offer, purchase two Digital Mind Coach e-books and get the third Digital Mind Coach e-book free.
Get more value with a discount.Limited Time Offer 33% Off.
Press Contact:
Perry Ritthaler
Digital Mind Coach
Writer
105-406-16th ave n
Creston, BC
Canada v0b 1g5
Tel: 2504285232
E-Mail: perry.ritthaler@digitalmindcoach.com
Web: http://www.digitalmindcoach.com
CRESTON, BC, January 15, 2011 -- Digital Mind Coach E-Books …Written By Perry Ritthaler, Published By Davis E-Book Publishing.
Discover How To Control Ideas, Decisions And Affirmations
http://www.digitalmindcoach.com $12.95 Canada 9.61 MB
Psychology - Self-Help - Over 120 Beautifully Full Colored Illustrations To Comfort The Thinking Mind- Learning how to control your ideas, your decisions, and your affirmations will quickly help you make positive, lasting and effective changes in your life, leading to personal empowerment, greater wealth, health and happiness. These are the most powerful psychological procedures for mind enhancement available in the world today.
Just by reading this e-book through a couple times, and with a little perseverance, you can build your confidence, increase your self-esteem, improve your mental focus and increase your ability to handle every day stress due to anxiety or tragedy. As importantly, you can greatly improve your performance in your work, enhance your everyday decision-making abilities, and elevate your mood in the process. Making the best decisions, having the best ideas, finalizing your affirmations, and gaining peace and comfort of mind are your final destination.
“Discover How to Control Ideas, Decisions and Affirmations” is a training manual which can help you move your life in a steadily positive successful direction. The affirmations and ideas presented here in pictures and text format are designed to enrich your life by opening the doors to the abundance of the Universe. This unique publication offer information and ideas which will help you to quickly make positive, effective and lasting changes in your life, leading to personal empowerment, and greater wealth, health and happiness.
The ideas are presented in such a way that positive thoughts soon become a natural part of your way of thinking. You will receive the benefits of a unique combination of the most powerful psychological procedures for mind enhancement available in the world today. The skills and techniques used in this e-book include advanced Psycho-Cybernetics and Neuro Linguistic Programming combined with Motivational Coaching.
By reading this e-book through a few times or so, and with a little perseverance, you can build your confidence, increase self-esteem, improve your mental focus and increase your ability to handle every day stress due to anxiety or tragedy. As importantly, you can greatly improve your performance in your work, enhance your everyday decision-making abilities, and elevate your mood in the process.
Imagine living the life you want!
If you can see it in your mind this e-book can help you make it a reality.
“Discover How to Control Ideas, Decisions and Affirmations” has been created to give people access to an internationally recognized approach to rapid behavioral change. The e-book can provide profound insights into the wealth of knowledge, wisdom and creativity that exists in each and every one of us. Through the use of this e-book people can lead more fulfilling, balanced and happier lives through understanding and utilizing the powerful motivating force of their subconscious mind.
Unlike life coaching, this e-book accesses the subconscious mind using pictures and written text to resolve issues quickly. The e-books offered through this web site are manuals to get more performance out of the brain and in doing so you can remove subconscious blocks, create a new belief system, tap into powerful resources and anchor your positive state of mind. It’s a powerful way to access your belief system and make the lasting changes you desire. Imagine feeling more empowered and having the mental tools to feel so much better.
The purpose of this e-book is to teach you how to accelerate the changes you want in your life and start becoming a better you by tomorrow.
Download your free sample e-book today.
Digital Mind Coach Promotion
We've Got More Value For You To Enjoy
More e-books. More fun. More value. Right now, there’s more of everything at Digital Mind Coach.
Limited time offer, purchase two Digital Mind Coach e-books and get the third Digital Mind Coach e-book free.
Get more value with a discount.Limited Time Offer 33% Off.
Press Contact:
Perry Ritthaler
Digital Mind Coach
Writer
105-406-16th ave n
Creston, BC
Canada v0b 1g5
Tel: 2504285232
E-Mail: perry.ritthaler@digitalmindcoach.com
Web: http://www.digitalmindcoach.com
Glenmore Healthcare Offers 10 Tips for Healthy Eating in 2011
One of the perennially popular New Year’s Resolutions is to loose weight, and the experts at Glenmore Healthcare, Calgary's premiere provider of hCG medically supervised weight loss programs, aesthetic medicine (Botox, Dermal Fillers, Latisse), offers dieters 10 Tips for healthy eating in the New Year.Calgary, Alberta, January 14, 2010 -- To help patients maintain their weight loss, the physicians at Glenmore Healthcare (http://www.glenmorehealthcare.com) offer the city's most successful hCG for Weight Loss program (http://www.glenmorehealthcare.com/our-program). hCG has been used as a weight loss aid for over 50 years, and is experiencing a resurgence in popularity in the US and Canada. Now, under the supervision of a physician at Glenmore Healthcare, patients can engage in this safe, effective weight loss program in Calgary.
Glenmore Healthcare's exclusive hCG Weight Loss Program is a proven medical solution for optimal weight loss and weight management. Based upon the successful protocol originally developed in 1954 by Dr. Simeons, and detailed in his manuscript, Pounds and Inches, the Glenmore Healthcare's hCG medically supervised weight loss program is built around a low calorie diet coupled with the administration of naturally occurring hormone, hCG (human Chorionic Gonadotropin). Glenmore Healthcare follows the IAPAM's (International Association for Physicians in Aesthetic Medicine) hCG Weight Loss Protocol, which has been administered to over 4,000 patients around the world with consistent weight loss results. The IAPAM's hCG Weight Loss Program is the only endorsed hCG weight loss protocol available to physicians.
After a successful weight loss, the experts at Glenmore Healthcare are committed to offering their patients enduring weight management strategies. Therefore, once a client has reached their goal weight, the protocol at Glenmore Healthcare includes a complete weight maintenance program, incorporating these tips to help patients maintain their new weight:
-Don't eat family style, you're much more likely to eat more than you would if you placed the correct portion size on a plate.
-Healthy restaurant menus may not be so healthy. You're likely to underestimate a meal’s calorie total by more than a third, according to a study in the Journal of Consumer Research.
-Alcohol makes you hungry (limit it to one or two glasses per meal)
-Restaurant portions are way too big, your choices are: (1) eat an appetizer, or (2) split an entre (either with another diner, or bring the other half home for another meal).
-Beware of office goodies. The office can be a source of 10-20lbs of fat per year. Skip the cakes, donuts, candies, and chocolates.
-Portion out your snacks. If you are going to have chips, read the bag and fill a bowl with a serving, then put the big bag away so you can't see it.
-Hungry an hour after a meal? Have a glass of water, or go for a brisk walk.
-Display fruits, not sweets. Get rid of the glass covered sweets display, and replace it with a fruit bowl.
-Researchers discovered that people who watched TV while they ate consumed nearly 300 more calories than those who dined without an eye on the tube.
-Slow down while you eat. If you consciously stop to take a breath between bites, you can cut your food (and calorie) intake by 10 percent, according to researchers at the University of Rhode Island. It takes 20 minutes for the news that you have had enough to eat to travel from your gut to your brain. Another tip, try talking more between bites.
For more "Tips for Weight Maintenance", go to http://www.glenmorehealthcare.com/weight-loss-tips.
For more information on hCG and weight loss, please contact Jeff Russell, Director, Glenmore Healthcare at 403-313-8328 or email info@glenmorehealthcare.com or to register for an hCG consultation, contact Angie at Glenmore Healthcare at 403-452-5699 or email info@glenmorehealthcare.com.
About Glenmore Healthcare
Glenmore Healthcare is Calgary’s premiere provider of hCG medically supervised weight loss programs, aesthetic medicine (Botox, Dermal Fillers, Latisse), health and wellness services to individuals in the Calgary area. For more information on Glenmore Healthcare's hCG program and aesthetic medicine and botox services, please contact Jeff Russell, Director, Glenmore Healthcare at 403-313-8323 or:
Glenmore Healthcare (Glenmore Landing)
A305, 1600 – 90th Avenue SW
Calgary, Alberta T2V 5A8
Ph: 403-452-5699
Fax: 403-452-7296
Websites
http://www.glenmorehealthcare.com
http://facebook.com/glenmorehealthcare
IAPAM Offers 10 Tips for Healthy Eating in 2011
To help physicians meet the needs of motivated patients, the IAPAM offers the industry's leading hCG for Weight Loss Training program (http://www.aestheticmedicinesymposium.com/physician-hcg-weight-loss-training). Attendees at the IAPAM's hCG Training learn from expert physicians, pharmacists and other specialists in the field of hCG and medical weight management, and are given all the tools, resources and instruction needed to profitably add hCG for Weight Loss to their practices right away.
The IAPAM is dedicated to offering physicians and their patients enduring weight management strategies, so once a patient has reached their goal weight, use these tips to help them maintain their new weight:
- Don’t eat family style, you’re much more likely to eat more than you would if you placed the correct portion size on a plate.
- Healthy restaurant menus may not be so healthy. You’re likely to underestimate a meal’s calorie total by more than a third, according to a study in the Journal of Consumer Research.
- Alcohol makes you hungry (limit it to one or two glasses per meal)
- Restaurant portions are way too big, your choices are: (1) eat an appetizer, or (2) split an entre (either with another diner, or bring the other half home for another meal).
- Beware of office goodies. The office can be a source of 10-20lbs of fat per year. Skip the cakes, donuts, candies, and chocolates.
- Portion out your snacks. If you are going to have chips, read the bag and fill a bowl with a serving, then put the big bag away so you can’t see it.
- Hungry an hour after a meal? Have a glass of water, or go for a brisk walk.
- Display fruits, not sweets. Get rid of the glass covered sweets display, and replace it with a fruit bowl.
- Researchers discovered that people who watched TV while they ate consumed nearly 300 more calories than those who dined without an eye on the tube.
- Slow down while you eat. If you consciously stop to take a breath between bites, you can cut your food (and calorie) intake by 10 percent, according to researchers at the University of Rhode Island. It takes 20 minutes for the news that you’ve had enough to eat to travel from your gut to your brain. Another tip, try talking more between bites.
The IAPAM's hCG Physician Weight Loss Training offers physicians a full-day of intensive education on the clinical best practices of hCG for weight loss, lipotropic injections and Very Low Calorie Diet (VLCD) programs. Physicians and their staff will learn the exclusive IAPAM hCG for Weight Loss Protocol (based on Dr. Simeons manuscript, Pounds and Inches.) The IAPAM's program gives physicians "everything they need to start offering medical weight loss programs to their patients immediately upon returning to their practices," emphasizes Jeff Russell, Executive Director of the IAPAM, and one of the IAPAM faculty instructors presenting at the IAPAM's hCG training. Also, the IAPAM's full day hCG training is the only hCG medical weight loss training in North America approved for a special medical malpractice coverage for those who have attended and have been certified by the IAPAM.
In 2010, all of the IAPAM's hCG Medical Weight Management seminars sold out, so to register for the next session in 2011, please see http://www.aestheticmedicinesymposium.com/physician-hcg-weight-loss-training, or contact the IAPAM at info (at) theiapam.com or 1-800-219-5108 ext 708.
About the International Association for Physicians in Aesthetic Medicine
The International Association for Physicians in Aesthetic Medicine is a voluntary association of physicians and supporters, which sets standards for the aesthetic medical profession. The goal of the association is to offer education, ethical standards, credentialing, and member benefits. IAPAM membership is open to all licensed medical doctors (MDs), dentists (DDSs/DMDs) doctors of osteopathic medicine (DOs), physicians assistants (PA’s) and nurse practitioners (NP’s). Information about the association can be accessed through IAPAM’s website at http://www.IAPAM.com or by contacting:
Jeff Russell, Executive-Director
International Association for Physicians in Aesthetic Medicine (IAPAM)
1-800-219-5108
info (at) theiapam.com
Websites:
http://www.IAPAM.com
http://www.IAPAM.com/botoxtraining
http://www.AestheticMedicineSymposium.com
http://www.aestheticmedicinesymposium.com/physician-hcg-weight-loss-training
http://www.iapam.com/hcg-for-weight-loss
http://www.iapam.com/hcg.html
Twitter: http://www.twitter.com/IAPAM
Facebook: http://www.facebook.com/IAPAM
IAPAM's hCG Group on Facebook: http://www.facebook.com/HCGWeightLoss
Physicians Rave about IAPAM's Symposium with Botox Training
Las Vegas, NV, January 12, 2010 -- Universally, physicians rave about the physician-lead training provided at the IAPAM's unique and respected Aesthetic Medicine Symposium (http://www.aestheticmedicinesymposium.com) and the associated hCG Physician Training. This is the only training program in North America to offer hands-on, live demo and didactic instruction covering botox training, laser training, hcg training, chemical peels, microdermabrasion, dermal fillers, and the business of adding aesthetic medicine to a practice - all in one weekend.
The International Association for Physicians in Aesthetic Medicine's (IAPAM) Aesthetic Medicine Symposium with botox training is different than any other educational program offered in North America. No other program in the U.S. offers this combination of comprehensive training in all the minimally invasive modalities in just 2 days. The IAPAM is where the world's physicians, of all medical specialties, come together to learn and share their experiences in aesthetic medicine. The IAPAM offers a suite of aesthetic medicine training programs from botox training to hCG training, along with aesthetic practice business training and membership in the IAPAM offers long term support to physicians adding botox, hcg and other aesthetic medicine treatment to a practice. Finally, unlike programs offered by a private company, attendees of the Aesthetic Medicine Symposium receive certification by the IAPAM, a voluntary professional association of physicians and supporters, which sets standards for the aesthetic medical profession.
Reviews from physicians tell the story. Since 2006, over 700 physicians have taken the IAPAM's aesthetic medicine training: Aesthetic Medicine Symposium, Physician (hCG) Medical Weight Management Training, Botox Training, Dermal Filler Training, Advanced Filler Training, and Chemical Peel Training, and here is what they have said:
-“An exceptional value, especially given the comprehensive amount of information provided. I’m most appreciative of the CD’s with all the [patient] forms, ads [and other marketing resources], and other info – all ready to be adapted and used immediately! An exceptional value for the money!” ~ Dr. Zgourides, MD (Dec ‘10)
-“This conference [the IAPAM's Aesthetic Medicine Symposium] was very informative and interesting. I really enjoyed all the speakers..and will most likely come back to another one with my staff. Great Conference. Thank you!” ~ Dr. Pino, MD (Dec ‘10)
-“[The hCG Training was] Absolutely beneficial! I would (and will!) recommend this conference to any colleague interested in prescribing hCG. The business implementation and marketing strategies were all so helpful!” ~ Dr. Cole, DO (Dec ‘10)
-“I learned how to add a successful hCG program to my practice and start a whole new adventure. I actually learned the tools to get started. Wonderful, motivating, informative, specific, intellectual. The best seminar I have attended. Wish I had brought my office manager.” ~ Dr. Jackson, MD (Dec ‘10)
-“Material needed for total program implementation is very good. Presented well in a simple, practical and implementable format.” ~ Dr. Gogineni, MD (Dec ‘10)
-“The whole course was especially interesting. The best CME/educational course I have attended.” ~ Dr. Brentnall, MD (Sept ‘10)
A preview of the IAPAM's Aesthetic Medicine Symposium can be viewed on YouTube at http://www.youtube.com/watch?v=Of-jMxVNLOY and IAPAM's Physician hCG Training.
IAPAM's hands-on botox training is offered in a multi-million dollar medical facility, not in a hotel room. Instruction on all the TOP 5 minimally-invasive procedures is lead by board-certified dermatologists and practicing physician experts. Join the hundreds of physicians who now have the IAPAM advantage. To register for an upcoming Aesthetic Medicine Symposium in 2011, please contact Lynn at 1-800-219-5108 ext. 704, lynn@iapam.com or visit http://www.aestheticmedicinesymposium.com/registration.
About the International Association for Physicians in Aesthetic Medicine (IAPAM)
The International Association for Physicians in Aesthetic Medicine is a voluntary association of physicians and supporters, which sets standards for the aesthetic medical profession. The goal of the association is to offer education, ethical standards, credentialing, and member benefits. IAPAM membership is open to all licensed medical doctors (MDs) and doctors of osteopathic medicine (DOs). Information about the association can be accessed through IAPAM’s website at http://www.IAPAM.com or by contacting:
Jeff Russell, Executive-Director
International Association for Physicians in Aesthetic Medicine (IAPAM)
1-800-219-5108
info@theiapam.com
Websites:
http://www.iapam.com
http://www.iapam.com/botoxtraining.html
http://www.AestheticMedicineSymposium.com
http://www.aestheticmedicinesymposium.com/physician-hcg-weight-loss-training
http://www.aestheticmedicinenews.com
http://www.aestheticmedicinesymposium.com/botoxtraining
http://www.aestheticmedicinenews.com/laser-training.html
Twitter: http://www.twitter.com/IAPAM
Facebook: http://www.facebook.com/IAPAM
Botox is a trademark of Allergan, Inc.
HIV Reservoirs Cure Research – More Investments Are Needed
Toulon, France, January 12, 2010 -- With great effort and research into how to fight the HIV virus, important advancements in treatment have been made. What used to be a near-automatic death sentence is no longer the case. With the right mixture of medicines, an HIV-positive person can now live much longer than before. The HIV asymptomatic periods are now much longer than before as well, thanks to HIV research. While all of this great work does not mean an outright cure has been found, the fact that HIV-positive people can continue to live normal lives means extraordinary progress has been achieved.
Antiretroviral therapy has been very successful in lengthening the diseases free periods in those who are HIV-positive; however, HIV infection persists for life, and every time therapy is stopped, the HIV rekindles and becomes active again. These HIV reservoirs of viruses must be dealt with. If left unchecked for too long, the mechanisms leading to full blown AIDS start again and severe health problems occur. Therefore, more HIV research is needed to attack these reservoirs with new medications, and that can only happen if more research and development can be put into the project. HIV suppression has worked so far, but additional research could yield a medication that targets directly the HIV latency period. We must be committed to funding additional research.
Without a preventive vaccine on the horizon, HIV’s pandemic is not controlled and could turn into something far more major and devastating. This isn’t just a problem in a few industrialized nations; HIV is a worldwide problem, and it’ll take a global effort to eradicate this terrible disease. Scientists can do their part by continuing to do research on new strategies against HIV; doctors can evaluate the effectiveness of each medication patients can continue to use these products and explain to the doctors what works and what doesn’t. Also, government agencies can make it easier for scientists by showing a real and concrete political will to cure the disease.
In addition to political and medical support, HIV research requires a fair amount of financial support. Developing new kinds of drugs takes some time and huge financial efforts, but with a global commitment, the HIV reservoirs can be dealt with in timely manner, the HIV latency period can be therapeutically targeted, which means reaching a ‘functional cure’ at least for millions of people living with HIV on a regular basis. While HIV persistence is inevitable in those who are HIV-positive, the right treatment will make it seem as if the virus is not affecting them at all, and one of the goals is to allow these HIV-positive people to lead as normal a life as they possibly can. With more time, effort, and financial support, we can also achieve a cure and total HIV eradication. However, that journey begins with a single step in the right direction.
About us: Dr. Alain Lafeuillade, Chair of the HIV Persistence and Reservoirs Workshop, Coordinator of the HIV Scientific Portal on HIV Reservoirs: http://www.hiv-reservoir.net
Contact:
Dr. Alain Lafeuillade
AVPS
1208 av Col. Picot. 83056
Toulon – France
+33-494616340
lafeuillade@orange.fr
http://www.hiv-reservoir.net
Antiretroviral therapy has been very successful in lengthening the diseases free periods in those who are HIV-positive; however, HIV infection persists for life, and every time therapy is stopped, the HIV rekindles and becomes active again. These HIV reservoirs of viruses must be dealt with. If left unchecked for too long, the mechanisms leading to full blown AIDS start again and severe health problems occur. Therefore, more HIV research is needed to attack these reservoirs with new medications, and that can only happen if more research and development can be put into the project. HIV suppression has worked so far, but additional research could yield a medication that targets directly the HIV latency period. We must be committed to funding additional research.
Without a preventive vaccine on the horizon, HIV’s pandemic is not controlled and could turn into something far more major and devastating. This isn’t just a problem in a few industrialized nations; HIV is a worldwide problem, and it’ll take a global effort to eradicate this terrible disease. Scientists can do their part by continuing to do research on new strategies against HIV; doctors can evaluate the effectiveness of each medication patients can continue to use these products and explain to the doctors what works and what doesn’t. Also, government agencies can make it easier for scientists by showing a real and concrete political will to cure the disease.
In addition to political and medical support, HIV research requires a fair amount of financial support. Developing new kinds of drugs takes some time and huge financial efforts, but with a global commitment, the HIV reservoirs can be dealt with in timely manner, the HIV latency period can be therapeutically targeted, which means reaching a ‘functional cure’ at least for millions of people living with HIV on a regular basis. While HIV persistence is inevitable in those who are HIV-positive, the right treatment will make it seem as if the virus is not affecting them at all, and one of the goals is to allow these HIV-positive people to lead as normal a life as they possibly can. With more time, effort, and financial support, we can also achieve a cure and total HIV eradication. However, that journey begins with a single step in the right direction.
About us: Dr. Alain Lafeuillade, Chair of the HIV Persistence and Reservoirs Workshop, Coordinator of the HIV Scientific Portal on HIV Reservoirs: http://www.hiv-reservoir.net
Contact:
Dr. Alain Lafeuillade
AVPS
1208 av Col. Picot. 83056
Toulon – France
+33-494616340
lafeuillade@orange.fr
http://www.hiv-reservoir.net
Author pursues Buddy Holly’s continuing impact on music and the lives of fans
Lake Forest, IL, January 11, 2011 -- Rock-and-roll pioneer Buddy Holly was just a kid from Lubbock, Texas, sporting black horn-rimmed glasses. Now, more than five decades after his tragic death, he and his music still affect lives around the world. The Iowa plane crash that killed him, The Big Bopper, and Richie Valens in 1959 is one of the most memorable plane crashes in history.
Gary W. Moore, the award-winning author of Playing with the Enemy, was born in 1954 but was not a fan of rock music. He knew nothing of Buddy Holly until he attended a tribute to him and his music by musician John Mueller in 2009. He was moved by the performance and astonished to learn that thousands of people of all ages around the globe are dedicated fans.
Hey Buddy: In Pursuit of Buddy Holly, My New Buddy John, and My Lost Decade of Music is Gary Moore’s chronicle of his personal journey to discover more about Buddy’s talent and character, his influence on generations of rock musicians, and the times in which he lived. He interviews people who were there the day of the crash, Buddy’s personal friends and family members, celebrities, and current-day Buddy enthusiasts. Hey Buddy examines our culture and how the young man from Lubbock brought us from where we were five decades ago to where we are today.
Along the way Moore discovers new information about the doomed charter flight that took off in bad weather with an inexperienced 21-year-old pilot. Himself a pilot, Moore and an aviation crash expert recreate the short flight. They conclude that the National Transportation Safety Board should re-open the crash investigation based on claims from the owners of the plane that the truth behind what happened that fateful night has never been told.
Hey Buddy: In Pursuit of Buddy Holly, My New Buddy John, and My Lost Decade of Music
By Gary W. Moore
List $25.00
ISBN: 978-1-932714-97-5
Published January 2011 by Savas Beatie LLC
Available at bookstores nationwide and online.
For more information and book tour schedule dates, visit http://www.heybuddybook.com
About Author Gary W. Moore
Gary W. Moore is an inspirational and motivational speaker, successful entrepreneur, accomplished musician, and award-winning and critically acclaimed author.
As author of Playing with the Enemy, Gary tells the story of his father, Gene Moore and his remarkable life in baseball and war. Playing with the Enemy will soon be a major motion picture. Gary is also a contributing author to the bestselling Chicken Soup for the Soul series and author of two upcoming books, Brimstone: The Dee Harper Story; and Carbon Hill.
Gary has been featured in publications such as Entrepreneur Magazine, Selling Power Magazine, Sales and Marketing Management Magazine, Impromptu Magazine, and Southwest Airlines’ Spirit Magazine, and has appeared on CNN, CNBC, ABC, NBC, CBS, and Fox.
Gary is a recipient of the prestigious Sam Walton Leadership Award and because of his unique speaking and writing style, has become known as “America’s Storyteller!”™
What People Are Saying
“Hey Buddy is a page-turning pursuit of Buddy Holly’s legacy and his impact on others in and out of the music industry. It’s as American as apple pie and as compelling as Don McLean’s legendary hit about The Day the Music Died. Run, don't walk, to your nearest bookstore and get two copies—one for you and another for anyone you know who listens to music.”
— James Riordan, New York Times bestselling author of Break on Through: The Life and Death of Jim Morrison
“Gary Moore’s Hey Buddy is a touching narrative that chronicles his fascinating journey of discovery into the life and music of Buddy Holly through the spirited performances of John Mueller while endeavoring to explain the profound impact Buddy’s musical legacy continues to have more than fifty years after his tragic demise.”
— Jacqueline A. Bober, Curator, The Buddy Holly Center
“Hey Buddy illustrates the raw power that passion for a topic can have when it grips an unsuspecting writer.”
— Bonnie Bartel Latino, author and former columnist for Stars and Stripes newspaper–Europe
Media review copies, ebook, high resolution photographs and interviews available upon request.
Contact:
Jim or Lynda O’Connor
O’Connor Communications, Inc.
Tel: 847-615-5462
E-Mail: jimo@oconnorpr.com
Web: http://www.oconnorpr.com
Gary W. Moore, the award-winning author of Playing with the Enemy, was born in 1954 but was not a fan of rock music. He knew nothing of Buddy Holly until he attended a tribute to him and his music by musician John Mueller in 2009. He was moved by the performance and astonished to learn that thousands of people of all ages around the globe are dedicated fans.
Hey Buddy: In Pursuit of Buddy Holly, My New Buddy John, and My Lost Decade of Music is Gary Moore’s chronicle of his personal journey to discover more about Buddy’s talent and character, his influence on generations of rock musicians, and the times in which he lived. He interviews people who were there the day of the crash, Buddy’s personal friends and family members, celebrities, and current-day Buddy enthusiasts. Hey Buddy examines our culture and how the young man from Lubbock brought us from where we were five decades ago to where we are today.
Along the way Moore discovers new information about the doomed charter flight that took off in bad weather with an inexperienced 21-year-old pilot. Himself a pilot, Moore and an aviation crash expert recreate the short flight. They conclude that the National Transportation Safety Board should re-open the crash investigation based on claims from the owners of the plane that the truth behind what happened that fateful night has never been told.
Hey Buddy: In Pursuit of Buddy Holly, My New Buddy John, and My Lost Decade of Music
List $25.00
ISBN: 978-1-932714-97-5
Published January 2011 by Savas Beatie LLC
Available at bookstores nationwide and online.
For more information and book tour schedule dates, visit http://www.heybuddybook.com
About Author Gary W. Moore
Gary W. Moore is an inspirational and motivational speaker, successful entrepreneur, accomplished musician, and award-winning and critically acclaimed author.
As author of Playing with the Enemy, Gary tells the story of his father, Gene Moore and his remarkable life in baseball and war. Playing with the Enemy will soon be a major motion picture. Gary is also a contributing author to the bestselling Chicken Soup for the Soul series and author of two upcoming books, Brimstone: The Dee Harper Story; and Carbon Hill.
Gary has been featured in publications such as Entrepreneur Magazine, Selling Power Magazine, Sales and Marketing Management Magazine, Impromptu Magazine, and Southwest Airlines’ Spirit Magazine, and has appeared on CNN, CNBC, ABC, NBC, CBS, and Fox.
Gary is a recipient of the prestigious Sam Walton Leadership Award and because of his unique speaking and writing style, has become known as “America’s Storyteller!”™
What People Are Saying
“Hey Buddy is a page-turning pursuit of Buddy Holly’s legacy and his impact on others in and out of the music industry. It’s as American as apple pie and as compelling as Don McLean’s legendary hit about The Day the Music Died. Run, don't walk, to your nearest bookstore and get two copies—one for you and another for anyone you know who listens to music.”
— James Riordan, New York Times bestselling author of Break on Through: The Life and Death of Jim Morrison
“Gary Moore’s Hey Buddy is a touching narrative that chronicles his fascinating journey of discovery into the life and music of Buddy Holly through the spirited performances of John Mueller while endeavoring to explain the profound impact Buddy’s musical legacy continues to have more than fifty years after his tragic demise.”
— Jacqueline A. Bober, Curator, The Buddy Holly Center
“Hey Buddy illustrates the raw power that passion for a topic can have when it grips an unsuspecting writer.”
— Bonnie Bartel Latino, author and former columnist for Stars and Stripes newspaper–Europe
Media review copies, ebook, high resolution photographs and interviews available upon request.
Contact:
Jim or Lynda O’Connor
O’Connor Communications, Inc.
Tel: 847-615-5462
E-Mail: jimo@oconnorpr.com
Web: http://www.oconnorpr.com
Green-Employers.com Helps Environmentally Aware Companies Find Like-Minded Employees
San Diego, CA USA, January 11, 2011 -- Green-Employers.com the job board that specializes in helping environmentally aware companies connect with like-minded job candidates, is the also one of the web’s leaders in delivering local job opportunities through newspaper partners nationwide.
“Plenty of large job boards have national opportunities but we have specialized at the local level. Everything from full and part-time jobs in a wide variety of careers and even work from home positions are available,” noted Sela Rodriguez, VP.
“Additionally our employers and job candidates are interested in green jobs with green companies. Employers are recognizing that to be good stewards of the environment you need to have staff that also share the same values.” Rodriguez added.
Green-Employers.com is also a great place for companies to market and brand their interest in the environment. If protecting our natural resources is important to a candidate, they are more likely to seek employment with a company that is engaged in energy conservation and environmental protection.
Companies can post their jobs at a very low rate of $45 per position and unlimited packages are available starting at only $995.
Candidates can search jobs and/or post their resumes for free. There is never a charge for job candidates on our website.
Green-Employers.com joins it’s partner websites http://www.IHireVeterans.com and http://www.Diversity-job.com in providing career opportunities to veterans, returning military and their families and offering a level playing field for all candidates to compete regardless of race, ethnicity, religion, gender, ability or sexual orientation.
Contact:
Sela Rodriguez
Green-Employers.com
E-Mail: Sela.Rodgriguez@JOB1.co
Tel: 619-575-6577
Web: http://www.Green-Employers.com
Diversity-Job.com Offers Great Local Career Opportunities
San Francisco, CA, January 08, 2010 -- Diversity-Job.com, the job board that specializes in helping diverse candidates and companies connect, is the also the web’s leader in delivering local job opportunities through newspaper partners nationwide.
“Plenty of large job boards have national opportunities but we have specialized at the local level. Everything from full and part-time jobs in Cosmetology, Dental Assisting, Sales, Engineering even work from home positions are available.” Noted Sela Rodriguez, VP.
Diversity-job.com is a discrimination-free zone. ALL candidates regardless of race, ethnicity, religion, gender, ability or sexual orientation are welcome.
“We believe that the term “diversity’ applies to so much more than race or skin color. Diversity is about giving every qualified candidate an equal opportunity to compete for available opportunities.” Rodriguez added.
Companies can post their jobs at a very low rate of $45 per position and unlimited packages are available starting at only $995.
Candidates can search jobs and/or post their resumes for free. There is never a charge for job candidates on our website.
Diversity-job joins it’s partner websites http://www.IHireVeterans.com and http://www.Green-Employers.com in providing career opportunities to veterans, returning military and their families and connecting candidates with environmentally aware companies. Become a friend of Diversity-job and Ms. Rodriguez on Facebook.
Contact:
Sela Rodriguez
Diversity-Job.com
Sela.rodriguez@JOB1.co
619-575-6577
http://www.Diversity-Job.com
Mattsonmaps Authors Rough Guide to Tourism Board Websites and Technology
Wenonah, NJ, January 07, 2010 -- To support recent launches of three new instances of a one-of-a-kind software application to promote destinations worldwide, Mattsonmaps shares a marketing study that is highlighted on an Tnooz.com, an international travel technology website.
Mattsonmaps President and former professor at Temple University in Philadelphia just published a white paper in the prestigious travel tech news site called tnooz.com. The White Paper, as summation of a market research study done in conjunction with the Rohrer Business School at Rowan University, surveyed 650 destination marketing organization to determine tool use and plans for tool acquisition. For the purpose of this study, Mattsonmaps defined tools as interactive and downloadable maps, events calendars, itineraries-builders, newsletters, coupons, slideshows, advertisements, and data mining utilities.
The survey was used to demonstrate a five-class taxonomy based on tool use, DMO size, and organizational staffing. It also recorded respondent commentary providing useful insights into otherwise statistical findings.
An early review of the article said, “[The article] is an early must-read for the year…”
Mattsonmaps found that DMOs fell into one or several of the following categories: (1) Capacity Under-Performers; (2) Technology Prisoners; (3) Widows and Orphans; (4) Big Men on Campus; and (5) Market Under-Performers.
Mattsonmaps Website: http://www.tools-for-travel.com/
Tnooz Article: http://www.tnooz.com/2011/01/04/how-to/rough-guide-to-tourism-board-websites-and-technology/
Mattsonmaps is a developer of Internet software tools applications for destination marketing organizations and affinity sites in specialized markets. For further information, please contact us at (856) 889-0102.
Contact:
Mark Mattson
President
Mattson Maps
307 N Jefferson Ave
Wenonah, NJ 08090
mark@mattsonmaps.com
856-889-0102
http://www.tools-for-travel.com
Mattsonmaps President and former professor at Temple University in Philadelphia just published a white paper in the prestigious travel tech news site called tnooz.com. The White Paper, as summation of a market research study done in conjunction with the Rohrer Business School at Rowan University, surveyed 650 destination marketing organization to determine tool use and plans for tool acquisition. For the purpose of this study, Mattsonmaps defined tools as interactive and downloadable maps, events calendars, itineraries-builders, newsletters, coupons, slideshows, advertisements, and data mining utilities.
The survey was used to demonstrate a five-class taxonomy based on tool use, DMO size, and organizational staffing. It also recorded respondent commentary providing useful insights into otherwise statistical findings.
An early review of the article said, “[The article] is an early must-read for the year…”
Mattsonmaps found that DMOs fell into one or several of the following categories: (1) Capacity Under-Performers; (2) Technology Prisoners; (3) Widows and Orphans; (4) Big Men on Campus; and (5) Market Under-Performers.
Mattsonmaps Website: http://www.tools-for-travel.com/
Tnooz Article: http://www.tnooz.com/2011/01/04/how-to/rough-guide-to-tourism-board-websites-and-technology/
Mattsonmaps is a developer of Internet software tools applications for destination marketing organizations and affinity sites in specialized markets. For further information, please contact us at (856) 889-0102.
Contact:
Mark Mattson
President
Mattson Maps
307 N Jefferson Ave
Wenonah, NJ 08090
mark@mattsonmaps.com
856-889-0102
http://www.tools-for-travel.com
Business Controls Hires Former Chief of Police as Vice President of Professional Services
Mr. Bennett will be responsible for overseeing the professional services department including investigations, training, and research and due diligence. Mr. Bennett will utilize his 30 years of experience in law enforcement, most recently working for the Colorado Department of Corrections Division of Adult Parole. Mr. Bennett has held numerous positions specializing in investigations, internal administrative affairs, vice/narcotics, gang task force units, and criminal investigation units.
“We are very excited to have Ricky here,” said Steve Foster, BCI’s President. “He brings a tremendous amount of expertise and experience to help our clients.”
Mr. Bennett holds two Masters of Arts degrees in Human Resources Development and Management and a Bachelor of Science degree in Criminal Justice Administration. He has completed curricula through the Federal Bureau of Investigation’s National Executive Institute and National Academy, as well as the Southwestern Law Enforcement Institute.
About Business Controls, Inc.
Business Controls, Inc. is the country’s leading incident reporting and risk mitigation firm. Its services include incident reporting, corporate investigations, litigation support, and training. Business Controls serves over a million client employees in over 22,000 client locations in 130 countries via its award-winning and patent-pending anonymous reporting systems. Business Controls puts clients in a position to be compliant with numerous governmental regulations and business ethics best practices, manage employee related issues, and limit their exposure to litigation. For more information, call 800-650-7005 or visit www.BusinessControls.com.
Contact:
Briggin Palmer
Marketing and Account Manager
Business Controls, Inc.
bpalmer@BusinessControls.com
800.650.7005
http://www.BusinessControls.com
International Efforts for a Society Free of AIDS: HIV Reservoirs Control
Toulon, IL, January 07, 2010 -- HIV and Aids have been around for 3 decades and yet, few diseases have ever had such a profound effect: it has taken the lives of millions of people and hit virtually every nation in the world. In addition, there is still no cure and Doctors and researcher are still fighting to create a society without AIDS.
All over the globe teams of scientists are actually dedicating their time and resources to finding a way to tackle HIV reservoirs as the virus survives hidden in these sanctuary sites despite therapy. What is it about this particular disease that makes it so difficult to cure?
HIV is impossible to eradicate because it establishes reservoirs. Although the disease can be slowed with antiretroviral therapy, HIV cannot be totally eradicated from the body. One of the main reasons is that HIV hides from drugs and immune surveillance in different organs and regions of the body, such as the brain and the gut. Doctors are not even yet able to determine and identify all the places where the disease can hide. HIV is also established in a dormant state in some reservoir cells where it can last for decades.
The ability of HIV to hide and remain silent makes some people wonder if the disease will ever truly be "cured" one day. Even if a sterilizing cure, i.e. getting rid of the virus in an infected individual, seems currently out of reach, other strategies of ‘control’ are on the horizon. First, by treating HIV infection very early, at the time of acute infection, up to 15% of patients can sustain HIV replication control after therapy is subsequently stopped. HIV is still present in these patients but remains silent, causing no harm, despite discontinuation of antiretroviral drugs. Therefore, they have been transformed in “Elite Controllers”, these rare cases of HIV infection (less than 1% of infected individuals) where the body itself is able to control the virus without medication. Then, some researchers are testing strategies to “purge” the reservoir. They give antiretrovirals to the patient to block HIV replication, but also other molecules able to stimulate HIV replication…in the cells where the virus is dormant. They hope to bring these cells to be destroyed or to die due to HIV expression, whereas healthy cells are protected by antiretrovirals.
To hasten progress in HIV reservoirs cure or control, a coordination strategy is urgently needed. In that way, we launched in 2003 an international HIV reservoirs workshop, dedicated to researchers, which also is a think tank on this topic. New scientific results relevant to tackling HIV persistence were presented at the second workshop in 2005, more clinical results were shown at the following editions in 2007 and 2009.
Whether eradicating the virus (HIV sterilizing cure) or achieving long-term remission in the absence of continued therapy (HIV functional cure) will be possible one day remains currently unknown. The categories of the workshop sessions span from animal models, identifying the locations of HIV reservoirs in the body, the mechanisms of viral persistence, to potential therapeutic interventions and methods to evaluate their impact.
In 2007 and 2009 we were joined in our fight against HIV reservoirs by institutional support, both from the NIH (American National Institute of Health) and the ANRS (French Agency for AIDS Research). The workshop was also accredited by the Massachusetts School of Medicine. The 2011 HIV reservoirs workshop will be held in December in Saint Martin.
About us: HIV Reservoirs and Eradication Strategies Workshop: http://www.hiv-reservoirs.com
Contact:
Ted Ias
AVPS
Toulon, IL, USA
Tel: 494616340
E-Mail: lafeuillade@orange.fr
Web: http://www.hiv-reservoirs.com
All over the globe teams of scientists are actually dedicating their time and resources to finding a way to tackle HIV reservoirs as the virus survives hidden in these sanctuary sites despite therapy. What is it about this particular disease that makes it so difficult to cure?
HIV is impossible to eradicate because it establishes reservoirs. Although the disease can be slowed with antiretroviral therapy, HIV cannot be totally eradicated from the body. One of the main reasons is that HIV hides from drugs and immune surveillance in different organs and regions of the body, such as the brain and the gut. Doctors are not even yet able to determine and identify all the places where the disease can hide. HIV is also established in a dormant state in some reservoir cells where it can last for decades.
The ability of HIV to hide and remain silent makes some people wonder if the disease will ever truly be "cured" one day. Even if a sterilizing cure, i.e. getting rid of the virus in an infected individual, seems currently out of reach, other strategies of ‘control’ are on the horizon. First, by treating HIV infection very early, at the time of acute infection, up to 15% of patients can sustain HIV replication control after therapy is subsequently stopped. HIV is still present in these patients but remains silent, causing no harm, despite discontinuation of antiretroviral drugs. Therefore, they have been transformed in “Elite Controllers”, these rare cases of HIV infection (less than 1% of infected individuals) where the body itself is able to control the virus without medication. Then, some researchers are testing strategies to “purge” the reservoir. They give antiretrovirals to the patient to block HIV replication, but also other molecules able to stimulate HIV replication…in the cells where the virus is dormant. They hope to bring these cells to be destroyed or to die due to HIV expression, whereas healthy cells are protected by antiretrovirals.
To hasten progress in HIV reservoirs cure or control, a coordination strategy is urgently needed. In that way, we launched in 2003 an international HIV reservoirs workshop, dedicated to researchers, which also is a think tank on this topic. New scientific results relevant to tackling HIV persistence were presented at the second workshop in 2005, more clinical results were shown at the following editions in 2007 and 2009.
Whether eradicating the virus (HIV sterilizing cure) or achieving long-term remission in the absence of continued therapy (HIV functional cure) will be possible one day remains currently unknown. The categories of the workshop sessions span from animal models, identifying the locations of HIV reservoirs in the body, the mechanisms of viral persistence, to potential therapeutic interventions and methods to evaluate their impact.
In 2007 and 2009 we were joined in our fight against HIV reservoirs by institutional support, both from the NIH (American National Institute of Health) and the ANRS (French Agency for AIDS Research). The workshop was also accredited by the Massachusetts School of Medicine. The 2011 HIV reservoirs workshop will be held in December in Saint Martin.
About us: HIV Reservoirs and Eradication Strategies Workshop: http://www.hiv-reservoirs.com
Contact:
Ted Ias
AVPS
Toulon, IL, USA
Tel: 494616340
E-Mail: lafeuillade@orange.fr
Web: http://www.hiv-reservoirs.com
Synergy By Jasmine Yoga, gives the edge to choose Romantic Valentine's Day Ideas near Philadelphia
A little online research will show that there are terrific retreats all over the globe. The abundance of differing techniques, varied locations and contrasting practices may be a bit overwhelming. Here is a checklist of considerations that might help finalize your choice, according to Jasmine Kaloudis, Yoga Retreat Leader near Philadelphia.
1. Instruction - Just as you know there are many forms of yoga, you also know each variation has a different instructional style. Make sure the teaching style at your retreat is to your liking and within you ability.
2. Goals - Make sure you understand the goals of the yoga retreat you will be engaging and that their goals match well with your personal aspirations. Again, research is the key. When setting your goals, think both long-term benefit and short-term benefit. If the program does not give you a sense of these benefits, speak to a coordinator.
3. Facility - Get an understanding of the program's facility and how the yoga program utilizes the retreat's facilities. Practical ramifications of this information may affect how you will dress and therefore the clothes you need to pack. Are you looking for something luxurious like Miraval or would something spartan, clean and more budget-friendly like Kripalu serve your needs?
4. Experience - Cross-reference your own research with the first hand or word-of-mouth experiences of previous attendees. Don't be afraid to ask if they would return or what their progress has been since visiting the retreat. Do a google search for reviews of the retreat or ask if you can speak with someone who experienced the retreat.
5. Travel - Just as you plan your itinerary, make sure there are no holes in your travel plans. Some retreats are in outlying areas. Verify and confirm all return-trip information weeks before departing. Check the weather as well before you are traveling. Investigate the cancellation policy in case of inclement weather.
6. Budget - Your budget should include all costs associated with travel and the yoga retreat.. Be especially clear about meal and travel provisions. It is safe to say that every yoga retreat has its own standards. Are extras such as spa treatments, mats, blocks and other classes included or are they extra?
7. Experience - Many yoga retreats cater to practitioners of different levels. Some retreats are prone to accept beginning students while others prohibit the beginner. Most important is matching your experience level with the program's stated experience levels. Are you looking to do an intensive program with 6-8 hours of yoga a day or would 2-3 hours be your pace? Find our the schedule before hand if you can.
Jasmine Kaloudis teaches yoga retreats at Synergy By Jasmine in Philadelphia. For free images of yoga poses with tips on how to do them, email info at jasminepartneryoga dot com with "Request Yoga Poses and Tips" in headline.
For more recent blog posts about mind, body, spirit topics and stress-management http://www.synergybyjasmine.com/blog
Twitter - synergyjasmine - Follow for inspiring quotes, vitality, meditation, yoga and stress-management.
Contact:
Jasmine Kaloudis
Public Relations
Synergy by Jasmine
3901 B Building Main Street, 2nd Floor
Manayunk, Philadelphia, PA 19127
Tel: 610.352.1177
E-Mail: info@synergybyjasmine.com
Web: http://www.synergybyjasmine.com
Biotage Announces New Methods for the Extraction of Key Compounds for Clinical, Environmental and Forensic Applications
“By offering SPE methods ready for use on the RapidTrace, labs are better able to quickly achieve consistent solid phase extraction results that meet industry needs for low to high throughput applications” says Anna-Karin Wihlborg, Biotage Product Manager. “These new methods further strengthen our portfolio of support illustrate that Biotage is committed to providing the tools our customers need to achieve greater results.”
The RapidTrace Workstation is the gold standard for efficient and reliable solid phase extraction from low to high throughput applications. Up to 10 RapidTrace Modules can be controlled simultaneously by one computer allowing for a scalable solution.
RapidTrace users can receive free software updates with the new methods pre-loaded by contacting a Biotage Representative. The RapidTrace utilizes effortless point-and-click software allowing for simple execution of pre-loaded methods as well as easy custom method set-up and editing.
Newly Released Methods for RapidTrace:
-Extraction of Vitamin D from Plasma Using ISOLUTE - This method allows extraction of the main active Vitamin D metabolites; 25-hydroxy-vitamin D and 1a, 25-dihydroxy-vitamin D. Deficiency can result in various disorders including osteoporosis, liver and kidney problems to increased risk of various cancers and multiple sclerosis, making this compound extremely clinically relevant.
-Extraction of the Cocaine Metabolite, Benzoylecgonine from Urine using ISOLUTE HCX - Due to short half life of cocaine, the screening for the presence of cocaine in urine is majorly accomplished via the major metabolite of cocaine; Benzoylecgonine. It allows a profile of use to be constructed and can be used to determine how long ago from the time of testing the cocaine was administered.
-Extraction of Tricyclic Antidepressants from Whole Blood Using ISOLUTE HCX Columns - Except for the use of Tricyclic antidepressants (TCAs) to treat depressive disorders, TCA’s have been found to have significant efficacy in the treatment of sleep disorders, ADHD, IBS and pain management.
-Extraction of Basic Drugs of Abuse from Biological Fluids using ISOLUTE HCX - The typical range of drugs screened using this generic method are Cocaine, D3 -Cocaine , Benzoylecgonine-TMS, D3-Benzoylegonine-TMS, Amphetamine, D5-Amphetamine, Methamphetamine, Codeine, Morphine, Amitriptyline HCL, Nortriptyline HCL, Imipramine HCL, Desipramine HCL. These drugs represent a panel of the most significantly abused drugs as recommended by The National Institute on Drug Abuse (NIDA).
-Extraction of Cyclosporine from Whole Blood Using ISOLUTE Columns - Cyclosporine is an immunosuppressant used in organ transplants to overcome rejection. Subsequent to an organ transplant, patients are tested at regular intervals for the presence of very low levels of the compound.
-Extraction of Environmental Contaminants Including Dioxins and Furans from Soil and Sediment Samples Using ISOLUTE NH2 – Dioxins and furans are a family of toxic chemicals. The levels of these chemicals in air, water and soil are constantly monitored through screening according to EPA guidelines, typical detection limits for these compounds in soil and sediments are 0.1 -1.0 parts per billion.
-Extraction of the Opiates, Morphine and Codeine from urine using ISOLUTE HCX - Morphine and codeine are two of the opiates analyzed in drugs of abuse testing, they are both on the SAMHSA (Substance Abuse Mental Health Service Administration) lists as drugs to be tested for workplace drug testing.
For more information regarding the application methods and the complete line of Biotage products for sample preparation, visit http://www.biotage.com
-Ends-
For further press information at Biotage please contact:
Rob Thompson
Director of Marketing Communications
10430 Harris Oaks Blvd., Suite C,
Charlotte, NC USA 28269
Tel: +1 704 654 4847
Fax: +1 704 654 4917
Email: rob.thompson@biotage.com
About Biotage
Biotage offers solutions, knowledge and experience in the areas of analytical and medicinal chemistry. The customers include the world’s top pharma and biotech companies, as well as leading academic institutes. The company is headquartered in Uppsala, Sweden, and has offices in the United States, United Kingdom and Japan. Biotage has 245 employees and had sales of SEK 394,1m in 2009. Biotage is listed on the NASDAQ OMX Nordic Stock Exchange. Website: http://www.biotage.com
IHireveterans.com Supports Military Veterans and Returning Military
San Francisco, CA, January 07, 2010 -- IHireveterans.com, the website designed to help US veterans and retuning military, has announced a new program to assist the families of these service members connect with willing employers. Named “Operation Homeguard” , the program aims at finding both professional and entry level opportunities for family members and vets.
With many thousands of jobs in careers nationwide like customer service, cosmetology, engineering, construction and even part time and work from home positions, Ihireveterans.com is a great choice for both employers and candidates.
“To that end we are offering employers an unprecedented opportunity to post their jobs for only $45. (Unlimited job posting packages starting at just $995.) This will help employers comply with EEOC regulations to conduct a concerted effort to recruit military veterans and retuning military, but to also help the service member’s families.” noted Sela Rodriguez, VP.
Persons seeking positions can post their resumes for free. “There is never a charge for veterans and families,” added Rodriguez.
Excellent opportunities are available nationwide in communities large and small. Ihireveterans.com is also supported by many local newspapers across the country offering positions that often never make the larger job boards.
Employers, service members, veterans and their families are invited to visit the site at http://www.IHireVeterans.com and find an exciting career opportunity or that next great employee. The website is partnering with it’s sister sites http://www.Diversity-Job.com and http://www.Green-Employers.com to create a comprehensive solution for employers and candidates.
Contact:
Sela Rodriguez
IHireVeterans.com
Sela.rodriguez@JOB1.co
619-575-6577
http://www.IHireVeterans.com
IAPAM's hCG Training Helps Physicians Meet Booming 2011 Weight Loss Demand
A recent report found that, "in January 2010, [internet search] terms related to weight loss such as “calories”, “calorie counters”, and “Body Mass Index (BMI)” were searched twice as often as they were in November and December of 2009....and diet programs were also popular searches." Equally, "people who explicitly made resolutions were 10 times more likely to attain their goals than people who did not," but up to 64% of resolutions are abandoned by Valentine's Day. To help physicians meet the needs of these motivated patients, the IAPAM offers the industry's leading hCG for Weight Loss Training program. Attendees at the IAPAM's hCG Training learn from expert physicians, pharmacists and other specialists in the field of hCG and medical weight management, and are given all the tools, resources and instruction needed to profitably add hCG for Weight Loss to their practices right away.
The IAPAM's hCG Physician Weight Loss Training offers physicians a full-day of intensive education on the clinical best practices of hCG for weight loss, lipotropic injections and Very Low Calorie Diet (VLCD) programs. Physicians and their staff will learn the exclusive IAPAM's hCG Training Protocol (based on Dr. Simeons manuscript, Pounds and Inches.) The IAPAM's program gives physicians "everything they need to start offering medical weight loss programs to their patients immediately upon returning to their practices," emphasizes Jeff Russell, Executive Director of the IAPAM, and one of the IAPAM faculty instructors presenting at the IAPAM's hCG training. The IAPAM weight loss course includes:
A detailed overview of the exclusive IAPAM hCG Protocol & best practice.
Understanding of VLCD/LCD diet programs.
-Patient selection criteria.
-Common medical contraindications.
-Current FDA status & requirements.
-Legal/Insurance considerations and special access to hCG Medical Malpractice Insurance Program.
-Weight Loss Practice Advertising & Marketing Tips and Strategies .
Attendees also receive the following program resources:
-Patient hCG Program book to offer patients (hCG friendly recipes, food journal, tips);
-Weight Management Practice Operational Manual;
-Patient Charting Forms, Medical History & hCG Consent Forms;
-Special Pricing for hCG and Meal Replacement Products; and
-hCG Waiting Room Presentations and advertising examples.
Finally, the IAPAM's full day hCG training is the only hCG medical weight loss training in North America approved for a special medical malpractice coverage for those who have attended and have been certified by the IAPAM.
In 2010, all of the IAPAM's hCG Medical Weight Management seminars sold out, so to register for the next session in 2011, please see http://www.aestheticmedicinesymposium.com/physician-hcg-weight-loss-training or contact the IAPAM at info (at) theiapam.com or 1-800-219-5108 ext 708.
About the International Association for Physicians in Aesthetic Medicine:
The International Association for Physicians in Aesthetic Medicine is a voluntary association of physicians and supporters, which sets standards for the aesthetic medical profession. The goal of the association is to offer education, ethical standards, credentialing, and member benefits. IAPAM membership is open to all licensed medical doctors (MDs), dentists (DDSs/DMDs) doctors of osteopathic medicine (DOs), physicians assistants (PA’s) and nurse practitioners (NP’s). Information about the association can be accessed through IAPAM’s website at http://www.IAPAM.com or by contacting:
Jeff Russell, Executive-Director
International Association for Physicians in Aesthetic Medicine (IAPAM)
1-800-219-5108
info (at) theiapam.com
Websites:
http://www.IAPAM.com
http://www.IAPAM.com/botoxtraining
http://www.AestheticMedicineSymposium.com
http://www.aestheticmedicinesymposium.com/physician-hcg-weight-loss-training
http://www.iapam.com/hcg-for-weight-loss
http://www.iapam.com/hcg.html
Twitter: http://www.twitter.com/IAPAM
Facebook: http://www.facebook.com/IAPAM
IAPAM's hCG Group on Facebook: http://www.facebook.com/HCGWeightLoss
The IAPAM’s Aesthetic Medicine Symposium with Botox Training Stands Alone
The IAPAM leads its competitors in offering the most complete botox training and aesthetic medicine education in North America. In 2011, attendees at the IAPAM’s Aesthetic Medicine Symposium will have the competitive advantage of learning from board-certified dermatologists and experts in the fields of botox training, lasers and light devices, dermal fillers, hCG for weight loss, medical grade chemical peels and medical micordermabrasion. Beyond the hands-on botox training and aesthetic medicine instruction, the resources physicians receive from the IAPAM position it as the most respected physician training available.Las Vegas, NV, January 05, 2011 -- The International Association for Physicians in Aesthetic Medicine’s (IAPAM) Aesthetic Medicine Symposium with botox training is different than any other educational program offered in North America. The IAPAM offers comprehensive aesthetic medicine training and long term support for physicians of all medical specialties. The IAPAM is where the world’s physicians come together to learn and share their experiences in aesthetic medicine. The IAPAM offers a suite of aesthetic medicine training programs from botox training to hCG training, along with aesthetic practice business training. Unlike programs offered by a private company, the Aesthetic Medicine Symposium is certified by the IAPAM, a voluntary professional association of physicians and supporters, which sets standards for the aesthetic medical profession.
Attendees at the IAPAM’s Aesthetic Medicine Symposium (http://www.aestheticmedicinesymposium.com) receive significant value for money. The Symposium provides physicians with:
- dedicated instruction from board-certified dermatologists, who are true experts of the skin and cosmetic injectables.
- hands-on practice in the best injection techniques.
- delivery of the botox training at a medical practice, not in a hotel room.
- an environment that does not allow exhibitors, giving doctors more time for education.
- the opportunity to attend the Symposium’s Aesthetic Practice Startup Workshop (http://www.iapam.com/bootcamp.html), which is the only medical spa program highlighting the latest information on medspa business development and social media marketing as taught by Harvard Business School.
- the unique opportunity to attend the full-day session on hCG and Medical Weight Management (http://www.aestheticmedicinesymposium.com/physician-hcg-weight-loss-training). This session will cover hCG for weight loss, prescription appetite suppressants, ketogenic diet based programs, meal replacement and B6/12 injections.
- a set of DVD’s from the Aesthetic Medicine Procedure Training series, which covers: Botox training, dermal filler training, and microdermabrasion training.
A preview of this training can be viewed on YouTube at http://www.youtube.com/watch?v=Of-jMxVNLOY.
To date, over 750 physicians, as well as their accompanying medspa managers, registered nurses, and assistants, have attended the IAPAM’s weekend Aesthetic Medicine Symposiums and hCG Physician Training sessions, which offer physicians a unique educational experience in a resort location from a renowned faculty. Join the hundreds of physicians who have the IAPAM Advantage! To register for an upcoming Aesthetic Medicine Symposium in 2011, please contact Lynn at 1-800-219-5108 ext. 704 or visit http://www.aestheticmedicinesymposium.com
About the International Association for Physicians in Aesthetic Medicine (IAPAM)
The International Association for Physicians in Aesthetic Medicine is a voluntary association of physicians and supporters, which sets standards for the aesthetic medical profession. The goal of the association is to offer education, ethical standards, credentialing, and member benefits. IAPAM membership is open to all licensed medical doctors (MDs) and doctors of osteopathic medicine (DOs). Information about the association can be accessed through IAPAM’s website at http://www.IAPAM.com or by contacting:
Jeff Russell, Executive-Director
International Association for Physicians in Aesthetic Medicine (IAPAM)
1-800-219-5108 ext. 704
info (at) theiapam.com
Websites:
http://www.iapam.com
http://www.iapam.com/botoxtraining.html
http://www.AestheticMedicineSymposium.com
http://www.aestheticmedicinesymposium.com/physician-hcg-weight-loss-training
http://www.aestheticmedicinenews.com
http://www.aestheticmedicinesymposium.com/botoxtraining
http://www.iapam.com/botoxtraining.html
Twitter: http://www.twitter.com/IAPAM
Facebook: http://www.facebook.com/IAPAM
Botox is a trademark of Allergan, Inc.
Young Entrepreneur Launches New Interactive Celebrity Gossip Website
New York, NY – January 5, 2011 -- Bill “sniper” Williams a Web entrepreneur forced to leave his previous job because of cutbacks and outsourcing has decided to start “another” Celebrity gossip Website, www.ezazz.com. The website www.ezazz.com will feature lead stories from the arrest of teachers from around the country.
The “celebrities” on www.ezazz.com are the teachers arrested for various offenses. The public needs to know where sexual predators and offenders are teaching. The site is designed for all types of schools from colleges, technical schools, universities, and more.
The public is also welcome to submit stories, opinions and facts. Www.ezazz.com has a very liberal removal policy. If someone asks that an entry about them is removed, we will consider it if there is good reason. As previously stated, if www.ezazz.com has information on an arrest, (although innocent until proven guilty) that person will appear on the website.
Students are encouraged to be “journalist” and send in fresh news content from their home town areas. New categories can always be added or created on www.ezazz.com.
Students are also encouraged to report on good teachers, professors and schools. Www.ezazz.com will moderate all incoming stories and comments.
Unlike the “other” social media websites, www.ezazz.com allows a user to post anonymous or their real information to post.
Www.ezazz.com will not post stories that are defamatory in nature, but an author's opinion or a news story will post on the website.
Www.ezazz.com can be viewed as a site in between thedirty.com and tmz.com only we combine both the news article and opinions into separate categories.
For more information log on to www.ezazz.com.
Contact:
Bill Sniper Williams
Ezazz.com
Newyork, NY
809-805-7881
Sniper@ezazz.com
http://www.ezazz.com
The “celebrities” on www.ezazz.com are the teachers arrested for various offenses. The public needs to know where sexual predators and offenders are teaching. The site is designed for all types of schools from colleges, technical schools, universities, and more.
The public is also welcome to submit stories, opinions and facts. Www.ezazz.com has a very liberal removal policy. If someone asks that an entry about them is removed, we will consider it if there is good reason. As previously stated, if www.ezazz.com has information on an arrest, (although innocent until proven guilty) that person will appear on the website.
Students are encouraged to be “journalist” and send in fresh news content from their home town areas. New categories can always be added or created on www.ezazz.com.
Students are also encouraged to report on good teachers, professors and schools. Www.ezazz.com will moderate all incoming stories and comments.
Unlike the “other” social media websites, www.ezazz.com allows a user to post anonymous or their real information to post.
Www.ezazz.com will not post stories that are defamatory in nature, but an author's opinion or a news story will post on the website.
Www.ezazz.com can be viewed as a site in between thedirty.com and tmz.com only we combine both the news article and opinions into separate categories.
For more information log on to www.ezazz.com.
Contact:
Bill Sniper Williams
Ezazz.com
Newyork, NY
809-805-7881
Sniper@ezazz.com
http://www.ezazz.com
HIV Reservoirs: Four main questions for 2011
Toulon, France, January 5, 2011 -- Despite effective antiretroviral combinations (HAART) capable of totally blocking the Human Immunodeficiency Virus (HIV) replication, this retrovirus persists life-long in patients due to the existence of hidden reservoirs. Major advances have been made since the first description of these HIV reservoirs in 1997 but a handful of fundamental questions remains to be elucidated before trying to find a cure.
Question 1: What is ‘the’ HIV Reservoir and Where is it Located?
The majority of the long-term HIV reservoir is situated in CD4+ T lymphocytes. These cells keep the memory of the immune system and are long-lived. We also know that within these CD4+ lymphocytes, the HIV reservoir is located in the central memory and transitional memory sub-populations. The HIV reservoir is 10 fold higher in the gut than in the blood and, in the brain, infected astrocytes could be the principal cells responsible for HIV persistence.
On the contrary, data on other HIV reservoir cells are scarce (Stem cells? Macrophages? Other sorts of cells?) as well as on different body compartments than the gut and the brain.
Question 2: What other factors than the virus play a role in the HIV Reservoir?
There are at least some recognized genetic factors and immune factors. For example, ‘elite controllers’ (patients controlling HIV replication themselves without the need of HAART) have a better CD8 antiviral response, leading to a kind of protection of the central memory CD4+ T cells, and this is associated with the presence of HLA B27 and B57 markers.
However, the exact nature of the immune response that could be able to control a very tiny HIV reservoir remains uncertain.
Question 3: What current HAART can do on the HIV reservoir?
The HIV reservoir is established very early, at the time of acute HIV infection. Treating HIV with HAART at the chronic stage of the disease is unable to decrease the HIV reservoir. However, it is highly likely that initiating HAART very early, at acute infection, limits the HIV reservoir size and the damages done to the immune system. Nevertheless, the clinical benefits of this early approach still need to be proven. It is also unknown if there is a threshold below which we can drive the HIV reservoir size and this one will not rekindle when HAART is discontinued. Finally, almost nothing is known on antiretroviral drugs activity in cells from different tissues.
Question 4: Can the HIV Reservoir be targeted and how?
The most advanced theory is the HIV reservoir ‘purge’, i.e. activating latently infected cells in the presence of HAART to make them die or killed by the immune system. The main candidates are Histone Deacetylase Inhibitors (HDACi) and Interleukin-7 (IL-7). There are concerns that IL-7 would not be strong enough to reactivate the HIV reservoir, or even help expand it, and that HDACi could put the brain HIV reservoir beyond control. Preliminary results of small pilot studies testing these new strategies are urgently needed.
About us:
Since the year 2003 we are committed in HIV reservoirs research and organize every 2-year the reference scientific workshop on HIV reservoirs. The next edition in December 2011 will address all these issues and much more (http://www.hiv-workshop.com).
Contact:
Alain Lafeuillade
CHITS
1208 Av. Col. Picot, 83056
Toulon, France
Ph: +33494616340
E-Mail: lafeuillade@orange.fr
Web: http://www.hiv-workshop.com
Question 1: What is ‘the’ HIV Reservoir and Where is it Located?
The majority of the long-term HIV reservoir is situated in CD4+ T lymphocytes. These cells keep the memory of the immune system and are long-lived. We also know that within these CD4+ lymphocytes, the HIV reservoir is located in the central memory and transitional memory sub-populations. The HIV reservoir is 10 fold higher in the gut than in the blood and, in the brain, infected astrocytes could be the principal cells responsible for HIV persistence.
On the contrary, data on other HIV reservoir cells are scarce (Stem cells? Macrophages? Other sorts of cells?) as well as on different body compartments than the gut and the brain.
Question 2: What other factors than the virus play a role in the HIV Reservoir?
There are at least some recognized genetic factors and immune factors. For example, ‘elite controllers’ (patients controlling HIV replication themselves without the need of HAART) have a better CD8 antiviral response, leading to a kind of protection of the central memory CD4+ T cells, and this is associated with the presence of HLA B27 and B57 markers.
However, the exact nature of the immune response that could be able to control a very tiny HIV reservoir remains uncertain.
Question 3: What current HAART can do on the HIV reservoir?
The HIV reservoir is established very early, at the time of acute HIV infection. Treating HIV with HAART at the chronic stage of the disease is unable to decrease the HIV reservoir. However, it is highly likely that initiating HAART very early, at acute infection, limits the HIV reservoir size and the damages done to the immune system. Nevertheless, the clinical benefits of this early approach still need to be proven. It is also unknown if there is a threshold below which we can drive the HIV reservoir size and this one will not rekindle when HAART is discontinued. Finally, almost nothing is known on antiretroviral drugs activity in cells from different tissues.
Question 4: Can the HIV Reservoir be targeted and how?
The most advanced theory is the HIV reservoir ‘purge’, i.e. activating latently infected cells in the presence of HAART to make them die or killed by the immune system. The main candidates are Histone Deacetylase Inhibitors (HDACi) and Interleukin-7 (IL-7). There are concerns that IL-7 would not be strong enough to reactivate the HIV reservoir, or even help expand it, and that HDACi could put the brain HIV reservoir beyond control. Preliminary results of small pilot studies testing these new strategies are urgently needed.
About us:
Since the year 2003 we are committed in HIV reservoirs research and organize every 2-year the reference scientific workshop on HIV reservoirs. The next edition in December 2011 will address all these issues and much more (http://www.hiv-workshop.com).
Contact:
Alain Lafeuillade
CHITS
1208 Av. Col. Picot, 83056
Toulon, France
Ph: +33494616340
E-Mail: lafeuillade@orange.fr
Web: http://www.hiv-workshop.com
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